Join us in the search for an effective hypertension therapy.

What is the purpose of the Brightn study?

The goal of the Brightn study is to see if the investigational study drug (CIN-107) can help lower blood pressure in people who are no longer responding to their current hypertension medications.

Who can take part in the Brightn study?

You can take part in the Brightn study if you meet the following:

  • You are an adult (at least 18 years old) with hypertension
  • You are taking hypertension medications on a regular basis
    • Note: You may have to adjust the types of medications you are taking to meet study requirements
  • You have a blood pressure of at least 130/80 but less than 180/110
  • You do not work night shifts

What will happen during the study?

If you choose to participate in the study, you can expect the following:

  • Screening period (up to 8 weeks). Visit the study clinic to find out if you qualify. You may need to adjust your hypertension medications during this period.
  • Run-in period (2 weeks). Take your hypertension medications and the study drug* daily for 2 weeks.
  • Treatment period (13 weeks). If you still qualify after the Run-in period, you will take your hypertension medications and the study drug* daily for 13 weeks and attend study clinic visits. During this period, neither you nor the study doctor will know what study drug you are taking.
  • Follow-up phone call (1 week). Receive a follow-up phone call from the study staff after your last study clinic visit.

* You will receive either the investigational study drug or a placebo (no active drug ingredients).