What is treatment-resistant hypertension?

Treatment-resistant hypertension is usually diagnosed when a person’s hypertension medications are no longer helping lower his or her blood pressure.

One potential cause of treatment-resistant hypertension is a build-up of a chemical called aldosterone, which helps regulate blood pressure. Many hypertension medications are designed to lower the amount of aldosterone in the body. However, aldosterone levels can sometimes increase even if you are taking medications to reduce it. This makes it difficult to control blood pressure.

The study drug is designed to work with your current medications to reduce aldosterone.